many years ago I had terrible iron deficiency and had to have Iron infusions. I got both Iron Dextran and Iron sucrose and was allergic to both but I had to keep getting them every 6 months because my numbers were so low. They premedicated me and did it in the hospital and admitted me for 3 -4 days each time. They were prepared for the reaction and as soon as I started having trouble breathing, I got breathing treatments, IV Steroids and lots of other medications. Luckily after 5 treatments I didn't need anymore and haven't needed it since. I had my RNY in October 2008 and I take Pruvate and so far my numbers are very good. I do see a hematologist every 4 months to make sure things are okay and my other doctors check me in between. The reaction isn't fun but if I need it again, Iwould get it again.