Thanks Mattie, that was a very informative post, lots of info. I am seeing my surgeon on 27th Sept, and a dietician, psycholgist etc, the cost is quite alarming but I feel definitely worth it, I feel like it is somebody else having it done and in no time at all I will be in having surgery (13th Oct).I am scared of all my comorbidities and find myself saying sometimes "why do I now have to have a big op on top of everything else", it overwhelms me sometimes, every week there seems to be another diagnosis. Am I allowed to mention the Drs name on here to see if anyone has been to him before? I won't unless someone tells me I can, thanks again, have you lost much weight and how are you coping now? Has the MS gone since stopping the med, how awful for you, I have heard it goes away when med is stopped. I was on Rituxan and had to stop due to allergic reaction same as enbrel, Orencia and most recently Actemra due to golden staph infection caused while on it, so stopped that now too, has been the story of my RA since day 1 so staying on steroids for last 10 years and MTX when I can tolerate it (between infections). Hope things improve for you and you have been a great help. God Bless and gentle hugs from Jane.