you'll be taking several batches of vitamins over the course of the day, so it is likely that one batch will be at bed time. As we are limited in the amount of absorbtion at a time, you may take calcium in four or five separate doses. And since zinc and iron canot be taken with calcium, you could have 7 doses over the day.
I have found most vitamins to be quickly disolvable so crushing wasn't necessary.
Some are better taken with food and some can come back up on you if you lay down too soon after taking them.
It will take a little while to sort out the best schedule for you.
good luck