sphincter of oddi and morphine

marilyn A.
on 10/15/12 10:35 am - willoughby, OH
DS on 03/17/94
I suffered a bad sphincter of oddi reaction after getting demerol during a liver biopsy a few years ago. Today a doctor told me that most ppl with sphincter of oddi dyssfunction can tolerate morphine......anyone tried it? He wants me to find a narcotic just in case I would uunexpectedly need one.





angelohio
ds i*****
Dr. Hess
235/140
P. Poster
on 10/15/12 1:49 pm
 ALL opioid narcotics can/will cause this issue, maybe not the first time you've had them, but possibly down the road.  I have the same issue, and have had to get creative when needing pain meds for anything.  I now have Toradol coadministered any time I need narcotics.  It is a smooth muscle relaxer and also works on the biliary system to prevent the spasms.  It's the only thing Ive found to work.  
marilyn A.
on 10/15/12 9:07 pm - willoughby, OH
DS on 03/17/94
Thanks Bean, I had Toradol yesterday with versed and propryphol for colonoscopy, and it worked like a charm. Is Toradol available as an oral agent? Up til now I've worked with a pain mgt doc who gives me Bentyl and then a pain killer (so far only fioricet) . That has also worked as I've had lead-in time to take the Bentyl and then wait 30min for painkiller. Have not tried anything stronger w/Bentyl yet.
HATE the sod reactions! But know I need to find something in case of an emergency

marilyn in ohio
ds i*****
235/140
P. Poster
on 10/15/12 11:04 pm
 I use Fioricet for my migraines, and have never had an issue with that particular med (Butalbital is a barbiturate not an opiate- so its not in the same family as those that have a known side effect of biliary tract spasm).  The opiates that can cause issue are- Morphine, Codiene, Dilaudid, Percocet (and all its variances), etc...  Yes, Toradol comes in pill form as well, I have a bottle I hang onto for rescue situations.  I've found that taking an OTC Zantact 150mg and a 10mg Toradol will knock most of these spasms (and associated gastric issue) right to the curb.  Good luck!
puppysweets1
on 10/16/12 2:06 am - CA
Can you explain waht a bad sphincter of oddi reaction means?

RNY to DS  210 lbs gone for 5 years.

maryc543
on 10/16/12 4:15 am

(copied...I had to look it up, too)

Sphincter of Oddi dysfunction is an uncommon condition that impairs the flow of bile and pancreatic fluids to the intestines. It can cause a number of uncomfortable symptoms, including nausea, vomiting, and sharp abdominal pains after eating. The disorder can occur if the sphincter is too narrow or becomes blocked due to inflammation, congenital abnormalities, or surgical complications. Doctors may be able to treat mild sphincter of Oddi dysfunction with prescription medications, but surgery is often necessary to ensure that problems do not return.

The sphincter of Oddi is a smooth, tubular muscle structure that opens into the duodenum, the upper part of the small intestine. It attaches to the pancreatic duct and the common bile duct from the gallbladder. The sphincter contracts and expands to regulate the flow of bile and pancreatic fluid into the duodenum, which helps to ensure proper digestion. In the case of sphincter of Oddi dysfunction, fluids back up into the ducts because the sphincter cannot relax and drain them.

Most doctors recognize two types of sphincter of Oddi dysfunction. Papillary stenosis refers to physical abnormalities that cause the sphincter to narrow. The most common cause is scarring due to bile or pancreatic duct inflammation. Scarring may occur if a person has gallstones or undergoes gallbladder, pancreas, or duodenum surgery. Congenital conditions may also affect the size and shape of the sphincter of Oddi.

 

The second type of sphincter of Oddi dysfunction is called biliary dyskinesia and involves changes in the sphincter's functionality. Sudden increases in bile duct pressure or adverse reactions to muscle-relaxing hormones can impair the muscle's ability to pump fluids. The causes of biliary dyskinesia are not well understood, but patients are more likely to develop the condition after undergoing gallbladder removal surgery.

Symptoms can vary depending on the severity of the disorder. Most people notice sharp, shooting pains in their upper abdomens, usually following big meals. A person may also experience frequent bouts of nausea, stomach cramps, vomiting, and loss of appetite. If the condition goes untreated, fluid backup can lead to pancreatitis and gallbladder inflammation. Symptoms tend to become more severe and constant once the organs are involved.

Doctors can usually diagnose sphincter of Oddi dysfunction by evaluating symptoms, counting liver and pancreatic enzymes in blood samples, and taking abdominal x-rays. If it is unclear what is causing fluid backup, a specialist can use an endoscopic camera to closely inspect the duodenum and sphincter.

Anti-inflammatory medications and a low-fat diet help some people recover from biliary dyskinesia. If the problem is structural, however, surgery is usually needed. A surgeon can implant a stent into the sphincter to hold it open and promote better fluid flow. Occasionally, the entire sphincter needs to be removed and the ends of the ducts are connected directly to the duodenum. Most patients are able to recover from surgery in less than three months and do not experience recurring issues.

DS Part 1 (VSG) 11/14/06 DS Part 2 12/18/07
HW 430 SW 400 CW 210 GW 170 Blog: lifeisgood-mc.blogspot.com

puppysweets1
on 10/16/12 6:45 am - CA
Thank you Marcy. Never heard of Shpincter of Oddi before and wondered where it was located.  This condition must be rather uncommon.

RNY to DS  210 lbs gone for 5 years.

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