Question:
Has anyone gained weight post op with antidepressants?

I had RNY bypass in 2001. I lost 180 lbs and held that steady for 5 years. I went thru menopause and had depression and anxiety. I was prescribed Effexor and have been on it since then. I have gained 60 pounds. I tried to ween off but still needed the drug. Could this be from the drug? Is there another drug that does not cause weight gain?    — clairewcouch (posted on January 21, 2009)


January 20, 2009
my only advise for you is to get back with the physician who prescribed the meds. If he/she will not listen to you, you may want to get a second opinion. you have worked too hard to just let the weight come back on. Good luck and I am sure there are med's out there that will not pack on the weight. I might also Google weight loss products on the internet to see which ones don't put on the weight. In the end, it is what we eat that puts the lbs on us. I fight that every day. Some days I win and other days I lose. I am trying to win more than lose. Susan
   — susangielda06

January 20, 2009
I am also on Effexor and losing just fine. Had RNY in Nov and down 50 pounds. So I don't know if it is the drug or if you just fell a little off the wagon. sorry about that but I just wonder if you have talked to your doctor about this. Sheri
   — sheri139

January 20, 2009
Effexor DOES cause weight gain according to my GP and psychiatrist, and they tell me that almost every anxiety and depression med they know of does. These meds are a HUGE contributor to my weight problems as they block my sense of satiation/ fullness, and can create cravings. I was on Epival for years, gaining about ten pounds a year according to my dr... before I found out Epival is also jokingly referred to as Epi-BLOAT !!! Now I am considering WLS with my GP dr and specialist but they are both VERY concerned about the weight gain from my meds (Effexor and Respiradone). I cannot go off of Effexor, unless they come up with a comparable med, minus the side effects. Anxiety disorder runs in my family and I know I will probably need these meds for life. There is a noticeable behavioral difference between family members who are on meds and those who are not... I don't want to live like those who are not treating their anxiety... I have already been there and my life- and stress levels- are WAY more productive and sane on Effexor... other than the awfulness of being morbidly obese, I have a very fulfilling life as a single parent, with a full time career, house, pets, male and female friends, great community etc. even some dating when I find the time...lol... Without anxiety meds my life was lived with constant hourly reactive stress, anxiety, panic attacks, edgy frenetic activity from feeling intensely pressured, and "tantrum outbursts" when constantly overwhelmed by my own perceptions of things big or small...then exhaustion and to bed or the couch in a inert zombie state for hours, and that is what some of my family members still live with. There are a couple of meds that have been found to sometimes suppress appetite in some patients, and cause weight gain in others... I think Topomax was one of those... but it depended on the patient. Sorry I don't have a better answer about living with anxiety meds... I have tried DOZENS for years at a time over the last 20 yrs. I have honestly had the best results for my mental health with Effexor and Respiradone, and I don't know how it will interact with WLS, so have not made my own decision... I was thinking about RNY, but don't know yet. My own doctors share my concerns, the bariatric ppl I ask seem TOO quick to re-assure that "it will be fine- now when can we book you?"!! If anyone can answer further to this issue, I am also interested. Sarah in GTA, Ontario, Canada
   — CinnSareLee

January 20, 2009
Hi, I was on efexxor for 3 years prior to my surgery and I did not experience any weight gain (maybe differnt for others)I had to stop taking it because I felt I took it so long it was not helping. I am now taking Zoloft which is working fine I may need to lower the dosage, because of weightloss. no weight gain.I am sure you know taking efexxor or any antidepressment do not just quit taking it I know especially with efexxor it will make you light headed and possible side effects and I thinking I was cured HAHA cause I was feeling so good stopped taking meds even recentlly and then WHAM depression is no fun.Best of luck Tammi
   — Tammi Sandoval

January 21, 2009
I take effexor and lexapro. My surgery date is March 6, 2009. Through the years, I have been on many antidepressants, but these seem to be the best for me. I have gained a lot of weight and I am very optimistic about the wls helping me. I hope since I am already on these meds that my surgery will bring me to my goals and the medicine doesn't affect it.
   — janet1150

January 21, 2009
I have been on Effexor for about 2 years, and gained weight, (pre WLS)but I don't think it was due to that medication. Prior to the Effexor, I was on Prozac (generic) and it suppressed my appetite. I think it depends on the patient. Maybe you should ask your doctor to recommend something different.
   — deejacobs

January 21, 2009
I know that Zoloft makes you gain weight and keeps you from losing it, but I believe that Effexor is in the same class. Ask you doctor if you can take Cymbalta. It does not interfere with your weight. Good Luck! Joyce
   — joycedev

January 21, 2009
Try to google the prescription online. It generally posts the side effects. There are very few that do not cause weight gain. CONGRATULATIONS on maintaining your victory!!!
   — bariatricdivalatina

January 21, 2009
Ask about getting wellbutrin and lexapro they are the least likely to make you gain weight. With wellbutrin you usually loss weight.
   — tamica D.

January 21, 2009
I too was on Effexor for a couple of years. I wanted off the medication due to a number of reasons, one of which was the weight gain. Effexor is difficult to get off due to the side effects of the withdrawal. My psych weaned me off with Prozac which worked out great. Good luck. Sue
   — yankeefan75

January 21, 2009
Effexor is often prescribed along with another med for weight loss by physicians. When I was on Effexor I lost weight (it was before my surgery). I was given Effexor to help me lose weight and although it helped a little and did not cause any gains, when the FDA issued a warning about it couple of years ago, my doctor took me off of it due to other health issues (which I no longer have since my surgery). Anyway, you might want to look at other areas and also talk to your doctor and surgeon about this weight gain. Best of luck to you. Cathy
   — brindledanes

January 22, 2009
I took Effexor XR after my medic partner was killed and was still on it 4 years later. It does cause weight gain and the side effects of the drug itself are tremendous. Effexor is a very difficult drug to ween off of because of the chemical change it has on your body. I ended up switching to Lexapro (without problems or side effects) and then weening off of that drug instead. MUCH easier transition and no weight gain with Lexapro. Best of luck to you.
   — Elizabeth J.

January 22, 2009
I would check with your doctor. If you aren't satisfied with the answers you get, keep fighting until you get the answer for yourself. I'm sure there are meds you can take that don't cause weight gain. Part of the problem you are talking about is your illness. I would do everything I could now before you gain more weight again-60 is easier to lose than 100 or more pounds. Try exercising too. Even a walk daily is helpful. Let us know what you find out we're listening. Good Luck and God Bless, vinnigirl, retired RN
   — vinnigirl

January 23, 2009
Ask your doc about Wellbutrin.
   — MAG

January 30, 2009
i'm not sure but i've been taking zoloft for a yr, & no gain! ask ur prescriber to switch
   — Melissa C.




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