Pizza-fied Chicken Casserole

Pizza-fied Chicken Casserole Recipe

July 8, 2022

Casseroles are family-dinner all-stars, and not just because of the multiple servings. The saucy, savory, comfort-food goodness is what makes those servings disappear every time! This Pizza-fied Chicken Casserole recipe deserves a prime spot in your personal casserole catalog. (Or is that not something normal people have?)

Pizza-fied Chicken Casserole

Recipe by: Lisa Lillien (a.k.a. Hungry Girl)
Makes 4 servings
Prep Time: 15 minutes; Cook Time: 40 minutes; Total Time: 55 minutes


  • 1 lb. raw boneless skinless chicken breast
  • 1/8 tsp. each salt and black pepper
  • 1/2 cup light/reduced-fat cream cheese, room temperature
  • 1/2 tsp. garlic powder
  • 1/2 tsp. onion powder
  • 1 1/2 cups chopped mushrooms
  • 3/4 cup chopped green bell pepper
  • 3/4 cup low-fat marinara sauce
  • 1/2 cup shredded part-skim mozzarella cheese
  • 3/4 oz. (about 12 slices) turkey pepperoni, roughly chopped
  • Optional topping: sliced black olives


  1. Preheat oven to 350 degrees. Spray an 8" X 8" baking pan with nonstick spray.
  2. Pound chicken to 1/2-inch thickness. Season with salt and black pepper. Bring an extra-large skillet sprayed with nonstick spray to medium heat. Cook for about 4 minutes per side, until cooked through. Transfer to a cutting board.
  3. Meanwhile, in a large bowl, combine cream cheese with 1/4 tsp. garlic powder and 1/4 tsp. onion powder. Stir until smooth and uniform.
  4. Remove skillet from heat; clean, if needed. Re-spray, and bring to medium-high heat. Add mushrooms and bell pepper, and sprinkle with remaining 1/4 tsp. garlic powder and 1/4 tsp. onion powder. Cook and stir until slightly softened and lightly browned, about 6 minutes.
  5. Transfer skillet contents to the bowl with the cream cheese mixture. Mix thoroughly.
  6. Chop chicken, and evenly place in the baking pan.
  7. Evenly top chicken with creamy veggies, marinara sauce, mozzarella, and chopped pepperoni.
  8. Bake until entire dish is hot and bubbly and mozzarella has melted, 20 - 25 minutes.

Nutritional Info Per Serving

Calories 294; Carbohydrates 9.5 grams; Fat 12.5 grams; Protein 35 grams

See more recipes on ObesityHelp by Lisa!

Pizza-fied Chicken Casserole


Lisa Lillien (a.k.a. Hungry Girl) is the creator of the Hungry Girl brand. She is the founder of, the free daily email service that entertains and informs hungry people everywhere. More than 1,000,000 fans eagerly wait for Hungry Girl’s recipes, food finds, and tips & tricks each weekday.
Read more articles by Lisa!
Recipe Disclaimer: If you have specific dietary restrictions, allergies or a nutrition plan that you are following, make sure to read the ingredient list prior to consumption. All information on is intended for informational purposes only. The information is not intended to be a replacement or substitute for consultation with a qualified medical professional. Please contact a medical professional with any questions and concerns.